Cultured Meats & Seafoods
Unlock alternative protein enhancement with accessible and validated gene editing tools for cells, microbes, and plants
Accessible Gene Editing for a Sustainable Future
Good Foods Institute
The Good Foods Institute (GFI) states that cultured and plant-based meats, along with microbial fermentation, can feed more people using fewer resources. To achieve this, optimizing cells, plants, and microbes for better yield, nutrition, and taste is essential. This is where precision gene editing comes in.
Cell Enhancement with Precise Cas-CLOVER
Targeted nucleases can remove, introduce, or edit genes at a predetermined location in the genome. When selecting a nuclease
technology it is important to account for both efficiency and precision. Cas-CLOVER nuclease, “the clean alternative to CRISPR/Cas9”, has fewer off-target mutations and less on-target rearrangements than CRISPR/Cas9.
Proven Stable Integrations with piggyBac Transposase
With over 300 peer-reviewed publications, piggyBac is recognized as the gold standard in stable protein production, cell immortalization, reprogramming, and differentiation. The beauty of piggyBac lies in its stable integration at highly expressed sites and footprint-free excision mechanism. PiggyBac is well validated in alternative food-based organisms, including chicken, cow, pig, goat, fish, and mollusks as well as yeast protein producer Pichia pastoris and lipid-dense Yarrowia lipolytica.
Outsource Your Pilot Study to Our Sister Company, Hera BioLabs
Demeetra's gene editing license starts with a simple evaluation period. For companies that would like to outsource their gene editing evaluation or cell line development, Hera is our preferred partner.
Hera helps researchers create cells with advanced traits for biomanufacturing at pharmaceutical grade quality. Leverage their experience with our gene editing technology in over 75 cell lines to complete your evaluation and possibly outsource all your future editing needs.
See How Scientists Are Using Our Gene Editing Tools
Elanco Research Scientist Kayla Bean, Ph.D, explored how Cas-CLOVER optimizes CHO cells for cell line development. These same principles can be applied to culturing foods with microbes.
Kayla Bean, Ph.D.
Research Scientist, Discovery Research At Elanco Animal Health
“Cas-CLOVER has several benefits to how the system works. The flexibility of the guide RNA design makes the system easy to use and gives a high specificity due to the use of two guide RNAs. It is very efficient due to the ability of the dead Cas9 to recognize the correct area of DNA, and since the Clo51 nuclease can only cut when dimerized the system has high fidelity.”
Optimizing Cultivated Meat Research and Development?
Contact us to learn more about our innovative gene editing technology.