Demeetra AgBio, Inc.

Demeetra AgBio, Inc.

CAS-CLOVER™: The clean alternative to CRISPR/Cas9 for bioprocess

By Demeetra AgBio, Inc. / February 4, 2020

Article Key Points Cas-CLOVER is a cleaner gene editing alternative to CRISPR/Cas9 for commercial bioprocessing Similar indel frequencies can be achieved as compared with CRISPR Cas-CLOVER is a highly specific system demonstrating no detectable off-targets Cas-CLOVER (and TAL-CLOVER) are covered by issued patents with clear freedom-to-operate Demeetra is offering evaluation licenses for Cas-CLOVER and GS…

Read More
Demeetra AgBio, Inc.

Knockout GS CHO cells in biologics manufacturing

By Demeetra AgBio, Inc. / January 22, 2020

Specific traits ranging from hearty growth & suspension culture scale up to cloning frequency have crowned CHO as the top bioprocessing host. However, due to low specific productivity during the cell line development and selection process, optimization of recombinant Chinese hamster ovary (CHO) cell line development for commercial bioprocess of therapeutic biologics such as antibodies,…

Read More