Demeetra AgBio, Inc.

Improving Protein Production in Tobacco With Gene Editing

By Demeetra AgBio, Inc. / September 24, 2020

Like yeasts, E. coli and other microorganisms, plants have long been useful tools to produce recombinant proteins through genetic modifications. The goals of these modifications vary from producing therapeutic proteins to making proteins for industrial use. However, genetically altering organisms to produce a protein of interest is a time consuming and labor intensive process, but…

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Modifying Tobacco Plants To Reduce Cancer Risk For Various Ethinic Groups Possible With Gene Editing

By Demeetra AgBio, Inc. / September 24, 2020

The link between smoking and cancer is well established; however, genetic variation leading to differential health outcomes across ethnic populations isn’t as clear. Genes Associated With Lung Cancer Research has shown that CYP2A6 and CYP2A13 gene variants are associated with a reduced risk of lung cancer among smokers of diverse ethnic backgrounds. These genes fall…

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Decreasing Carcinogen Levels in Tobacco With Gene Editing

By Demeetra AgBio, Inc. / September 1, 2020

Tobacco has been cultivated for hundreds of years and a source of income for many around the world. It’s not only found in the modern day commercially sold cigarette that includes several other ingredients besides tobacco, but is also consumed in the form of cigars and hookahs. And, some even roll their own tobacco which…

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Seedless Fruit Production With Gene Editing

By Demeetra AgBio, Inc. / August 20, 2020

Parthenocarpy (the production of seedless fruit without prior fertilization) occurs in nature whether through a mutation that leads to negative consequences or as a benefit to shield against predators. It can also be exploited by scientists to achieve produce with longer shelf- lives or for practical purposes; such as large scale sauce production, or more…

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The Significance of Genetically Modifying Glutamate in Plants

By Demeetra AgBio, Inc. / August 19, 2020

As the population continues to grow and food production becomes more difficult due to weather patterns, disease, and lack of nutrient rich land, better solutions are needed. It is the hope of many scientists all over the world that genetically modifying plants and animals will assist with the challenges that we face, specifically wipe out…

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Gene Editing for Long-Lasting Fresh Tomatoes

By Demeetra AgBio, Inc. / August 14, 2020

In our modern society where we visit the grocery once a week versus daily, keeping produce fresh is a challenge. It’s a challenge worth investing in due to not only the economic value, but the nutritional importance as well. Modern gene editing technology is allowing for many advantages such as longer lasting storage of produce;…

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Demeetra AgBio, Inc.

CAS-CLOVER™: The clean alternative to CRISPR/Cas9 for bioprocess

By Demeetra AgBio, Inc. / February 4, 2020

Article Key Points Cas-CLOVER is a cleaner gene editing alternative to CRISPR/Cas9 for commercial bioprocessing Similar indel frequencies can be achieved as compared with CRISPR Cas-CLOVER is a highly specific system demonstrating no detectable off-targets Cas-CLOVER (and TAL-CLOVER) are covered by issued patents with clear freedom-to-operate Demeetra is offering evaluation licenses for Cas-CLOVER and GS…

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Demeetra AgBio, Inc.

Knockout GS CHO cells in biologics manufacturing

By Demeetra AgBio, Inc. / January 22, 2020

CHO Cells – An essential tool for biopharma Traits like robust growth, easy scaling of suspension cultures, and reliable cloning frequency have crowned Chinese hamster ovary (CHO) cells as an ideal mammalian cell line for bioprocessing. However, optimizing recombinant CHO cell development to produce biologics like antibodies can still be quite the challenge.   DHFR…

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